Teaching supervisor: Francoise Ochsenbein, Anatole Chessel

Prerequisite: BIO_1S001_EP

This course, BIO_2F001_EP, entitled "Macromolecules in Their Environment", explores the specific features of biological macromolecules and how they perform their functions in living systems. An in-depth introduction to experimental and computational methods for determining and predicting their structure provides insight into how molecular-level information is essential for understanding key biological mechanisms, as well as for designing new active molecules with applications in health and environmental sciences. The course then introduces core concepts in cellular and developmental biology, enabling students to abstract and model biological processes at both the cellular and multicellular levels. It highlights the interdisciplinary contributions of physics, chemistry, and computer science to our understanding of life. Each session is complemented by hands-on computer-based practicals, built around concrete, progressive examples.

Course Language : English.   

Prerequisite: BIO_1S001 & BIO_2F001

Molecular Genetics (BIO_2S002_EP) provides an in-depth understanding of the mechanisms by which living organisms store, express and transmit genetic information and the basis of human genetic diseases. Lectures will cover a range of topics, including the molecular aspects of DNA replication and transcription, translation of RNA into protein and gene regulations. This course will also cover the latest methodologies used in genomics analysis, like DNA sequencing. Because experimentation is at the heart of progress in cell biology, 50% of classes contain practical work, completed over the course of the semester. The intention is to allow students to develop their knowledge in the subject area, to acquire sound scientific reasoning, and to combine the modern techniques in molecular genetics with computer-assisted data analysis.